Antibody modification

Antibody conjugation involves attaching specific molecules, such as fluorochromes, enzymes, or drugs, to an antibody to enhance its functionality.

• Conjugation with fluorophores for microscopy and flow cytometry.
• Attachment of drugs for antibody-drug conjugates (ADCs) in targeted therapy.
• Addition of labels for diagnostic and imaging applications.

Our conjugation services ensure high specificity and preservation of the antibody’s biological activity, tailored to your experimental requirements.

Antibody fragmentation produces functional fragments, such as Fab or F(ab’)2, for applications requiring smaller size or specific binding properties.

• Generation of Fab fragments for enhanced tissue penetration.
• Production of F(ab’)2 fragments for studies without Fc-mediated interactions.
• Customization for immunology and diagnostic applications.

Our fragmentation processes utilize specific enzymes and rigorous quality controls to ensure optimal purity and functionality.

Antibody engineering modifies the structure of antibodies to optimize properties such as affinity, specificity, or stability.

• Development of bispecific antibodies for dual targeting.
• Humanization to reduce immunogenicity in therapeutic applications.
• Fc domain optimization to enhance effector functions.

Our engineering services rely on advanced recombinant techniques, delivering tailored antibodies for research and clinical applications.

Antibody purification is critical for obtaining high-purity products free of contaminants, suitable for sensitive applications.

• Affinity chromatography for high specificity.
• Endotoxin removal for in vivo studies.
• Validation through HPLC and SDS-PAGE for quality assurance.

Our purification protocols are optimized for reproducibility and regulatory compliance, essential for your research projects.