Case studies
Chemical Synthesis of Cytokines and Interleukins
While recombinant expression has long been the standard for producing cytokines, chemical synthesis is emerging as a powerful alternative. This case study explores how bypassing biological systems allows for the creation of highly pure, precisely modified cytokines—entirely free from endotoxins and batch-to-batch variability. Discover how this innovative approach is unlocking new potential in immunology research and therapeutic development.
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Chemical synthesis of VHHs: Advanced therapeutic formats
VHHs, also known as nanobodies or single-domain antibodies, have emerged as clinically validated therapeutic formats with exceptional potential in oncology, immunology, and targeted therapies. As demand grows for complex, homogeneous, and precisely modified VHHs, chemical synthesis offers a powerful alternative to traditional recombinant production. This approach enables unparalleled molecular control, site-specific functionalization, and rapid development of advanced formats such as multivalent constructs, drug conjugates, and radiolabeled molecules.
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Successful Synthesis of Pure And Perfectly Structured Interferon Alpha-2a by Chemical Protein Synthesis
Interferon Alpha-2a (INF Alpha-2a) is a type 1 interferon that consists of 165 amino acid residues, which is a therapeutic mid-size protein, is traditionally produced by recombinant technology. This cytokine is extensively used for its antiviral and antineoplastic properties. 1. Chemical Protein Synthesis Chemistry offers endless possibilities for producing custom proteins. Our technology makes it possible to build molecules atom by...
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